Synthesis, Table of Contents Synthesis 2024; 56(10): 1648-1656DOI: 10.1055/s-0042-1751559 paper Convenient Synthesis of Hexa- and Pentasaccharide Repeating Units Corresponding to the O-Polysaccharides of Acinetobacter baumannii O7 and Acinetobacter baumannii O10 Strains Authors Samim Sahaji Puja Bag Anup Kumar Misra∗ Recommend Article Abstract Buy Article(opens in new window) All articles of this category(opens in new window) Abstract The synthesis of the hexa- and pentasaccharide repeating units of the cell wall O-polysaccharides of Acinetobacter baumannii O7 and O10 strains, respectively, has been achieved in very good yield using [4+2] and [4+1] block glycosylation strategies. The p-methoxybenzyl (PMB) group was used as an in situ removable protecting group, which was removed after glycosylation in the same pot by tuning the reaction condition. A challenging β-l-rhamnopyranosyl linkage was constructed using ‘armed-disarmed glycosylation’ conditions by the influence of a remotely located, H-bond mediating, picolinoyl group in the glycosyl donor. A d-mannosamine intermediate was prepared from d-glucose using minimum reaction steps. The hexa- and pentasaccharide were achieved as their p-methoxyphenyl (PMP) glycosides. Key words Key wordscarbohydrates - glycosylation - glycoside - oligosaccharide - synthesis Full Text References References 1a Khan HA, Baig FK, Mehboob R. Asian Pac. J. Trop. Biomed. 2017; 7: 478 1b Larsen EN, Gavin N, Marsh N, Rickard CM, Runnegar N, Webster J. Infect. Control Hosp. Epidemiol. 2019; 40: 1100 2a Abalkhail A, Alslamah T. Vaccines (Basel, Switz.) 2022; 10: 1811 2b Ferronato N, Torretta V. Int. J. Environ. Res. Public Health 2019; 16: 1060 3a White MC. J. Clin. Epidemiol. 1993; 46: 95 3b Dadgostar P. Infect. 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